Pharmaceutical pollution is an emerging concern in the world. Major manufacturing units of pharmaceutical companies are successfully running in the developed countries like the USA, UK, Canada, Germany, Australia, Ireland, and Japan and the developing countries like China, India, Brazil, Argentina, and Thailand. Pharmaceutical compounds are entering into the ecosystem finally end up in the drinking water as well as in the food web. Excessive usage of antibiotics for animals, as well as human beings, generates superbugs, this is the root cause of superbug crisis and untreated superbug infection. This review proposed the current scenario of pharmaceutical waste and its effects globally. Furthermore, it compile the pharmaceutical pollution in soil, water resources, and also discussed the suitable treatment process