The automotive sector has been experiencing a rapid development in recent times. Modern trends aim at the progress of so-called sustainable, eco-friendly vehicles, in many cases associated with advanced technologies and assistance systems. It is increasingly common to see cars with electric, hybrid, gas or hydrogen propulsion systems. Such approaches can create a transformation of manufacturing processes towards the growth of new types and fields of technologies and systems in the automotive industry. The manuscript discusses the subject of vehicles with various types of power supply, i.e., propulsion system. The investigation was executed with different respondent groups whereby the analysis was performed predominantly by using two merging criteria such as place of residence and gender of respondents. Following the research conducted, we state that given a variety of variables, the majority of the respondents are convinced that, prospectively, electric and hybrid vehicles in all probability will be the prevailing types of vehicles occurring on the roads of the Czech Republic. However, it is also important to analyze the situation of the current access to energy resources for manufacturing of both kinds of vehicles and, above all, their utilization. Thus, the preferences of drivers are key issues, but it is also necessary to take into consideration the production capacity and investment profitability regarding the purchase of vehicles with modern types of propulsion system.