‘Cerason’ is an interspecific cultivar of grapevine that has been bred and selected in the Czech Republic (2008). The cultivar is a result of crossing the cultivars ‘Merlan’ and ‘Fratava’ and shows very promising potential within the framework of a fungus-resistant (PIWI) cultivar, making it particularly suitable for organic wine- making. This paper presents the results of an experiment performed with seven selected rootstock cultivars (viz. ‘Kober 125AA’, ‘Amos’, ‘Börner’, ‘Crâciunel 2’, ‘Kober 5BB’, ‘K1SO4’ and ‘Teleki 5C’) and some data about the effects of these rootstocks on the quantitative variables of the cultivar ‘Cerason’. The aim of this study was to choose and specify the rootstock cultivars that would be the most suitable for a given locality. The following traits were monitored and recorded: plant vitality, the yielding capacity of the individual plants, and the number and weight of clusters per vine. The weight of 100 berries was also an important variable. The rootstock cultivars ‘Kober 125AA’ and ‘Kober 5BB’ were evaluated as the best for optimal growth and fertility (especially a higher fertility index, pruning weight and weight of clusters). The experimental results indicated that the cultivar ‘Crâciunel 2’ could also be a suitable rootstock. The ‘Kober 125AA’ rootstock also showed the most optimal Ravaz index, with an average of 5.9 over the three-year observation period.