Climate variability is a major challenge concerning food security; therefore, there is a need for pragmatic solutions to improve agricultural production. Henceforth, this study was planned to optimize the planting time of exotic safflowers under the prevailing conditions in Faisalabad, Pakistan. A study was executed by employing a split-plot design with six safflower accessions and five sowing dates ranging from 31 October 2019 to 31 December 2019. The results of the experimental safflower accession PI-198990 produced significant seed yields (2432 kg ha−1, 2772 kg ha−1 and 2366 kg ha−1) when sown on 30 November 2019, 15 December 2019, and 31 December 2019, respectively. On the other hand, on 31 October 2019 and 30 November 2019, sown safflower accessions PI-208677 and PI-250187 were the best performers, respectively. However, a higher achene oil percentage (31.5% and 30.8%) was noted in accessions PI-250187 and PI-314650 when sown on 31 December 2019 and 15 December 2019, respectively. The highest oleic acid content (22.92% and 22.83%) was determined in accession PI-314650 when planted on 30 November 2019 and 15 December 2019, respectively, whereas a higher linoleic acid content was observed on 31 October 2019 and 30 November 2019. Stability analysis showed that safflower accession PI-210834 was the most stable under all sowing environments, followed by PI-314650. Correlation analysis showed that oil percentage showed a negative correlation with phenological traits and growing degree days, and oil yield showed a strong positive relationship with heads, seed yield, biological yield, thousand seed weight, and harvest index.