The aim of the study was to determine the nutritional value (content of endogenous and exogenous amino acids) and safety (content of metals and radionuclides) of the muscle tissue of fish obtained in the Shuchinsk- Burabay recreation area (Kazakhstan). Analytical methods involving mass spectrometry with inductively coupled plasma and liquid chromatography were used. The content of exogenous amino acids in fish protein was similar to their level in the meat of cattle, pigs, and poultry obtained in the same leisure zone. The ratio of the sum of exogenous amino acids to the sum of endogenous amino acids in fish meat protein ranged from 0.29 to 0.39. In all samples, it ranged from 45.45 to 33.33% of the norm. Samples of fish meat from some lakes diverged from the norm in the amount of exogenous and endogenous amino acids by 2.01-3%. Valine was a limiting amino acid in the meat of fish from all lakes; its amount ranged from 21.6 to 27.8%. The second most important limiting amino acid was isoleucine, which ranged from 72.1 to 77.25%. The contents of heavy metal salts were up to 0.0590 mg/kg for arsenic, 0.0050 mg/kg for cadmium, and 0.0350 mg/kg for lead, which did not exceed the norms of the maximum allowable concentration of these metals. Only the mercury content in perch muscle tissue, which was 0.0385 mg/kg, exceeded the maximum permissible concentration by 28%. The level of other metals was in line with the standards. Fish from the lakes of the Shuchinsk-Burabay recreation area are slightly contaminated with heavy metal salts, but these pollutants generally do not exceed the maximum permissible concentration. The concentration of radionuclides in fish samples did not exceed the maximum permissible level.